How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Summary

We are looking for a highly motivated PhD-trained individual for a postdoc position and team player with a strong interest in understanding the cancer biology of leukemia and early T-cell development/regeneration with a goal to develop the basic science foundation needed to improve the effectiveness and safety of current medical treatments. Please see our website for additional details: http://chiangmarky8.wix.com/chiang-lab

Specific methodologies include (but not limited to):

• Protein-protein and protein-DNA interaction biochemistry (mass spectrometry, co-immunoprecipitation; ChIP; reverse-ChIP, NMR)
• Transcriptional genomics (ChIP-Seq/ATAC-Seq library preparation; RNA preparation for RNA-Seq library preparation; computational analyses of sequencing data using existing pipelines; basic bioinformatics)
• Transcription factor assays (reporter; CRISPRi; ChIP; gel shift; qRT-PCR)
• Early T-cell development and leukemogenesis assays (flow cytometry sorting and analysis; histology; bone marrow transplantation; intrathymic injections; retroviral transduction and transplantation; in vitro stromal cell culture; transplantation in NSG mice)

Model systems include:

• Genetically engineered mouse models (Cre-loxP)
• Human leukemia patient-derived xenograft models
• Human and mouse leukemia cell lines

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• Retirement Savings Opportunities

Responsibilities*

• Design, perform, analyze, and interpret experiments with a level of supervision from PI and other lab members in line with existing skill set with goal towards independence
• Work as a team with other lab members, such as the bioinformaticist and the lab manager/work-study students who manage the mouse colony and maintain the lab
• Supervise undergraduate and rotation students
• Train other lab members as needed
• Collaborate with members of other labs as needed
• Write first-authored manuscripts for publication
• Write first-authored abstracts for intramural/extramural research conferences
• Generate and present posters and give talks at lab meetings, combined lab meetings, and intramural/extramural research conferences
• Travel to research conferences and other labs outside the university as needed

Required Qualifications*

PhD in a biomedical field

Desired Qualifications*

Experience in genetically engineered mouse models or protein biochemistry or transcription factor assays

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

Vaccine Requirements

COVID-19 vaccinations are required for all students, faculty and staff working in the following areas: Michigan Medicine including the Medical School, Dental School, University Health Service or the Mary A. Rackham Institute. This includes those working remotely and temporary workers. More information on this new policy is available on the U-M Health Response.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.