Roche is seeking a motivated and team-oriented individual who is passionate about the possibilities of next-generation sequencing. Working with cross-functional teams, you will become an expert in the theory of operation of the nanopore DNA sequencing system and will play a key role in the successful transition of these technologies from an advanced proof of concept into the product phase. As a Principal System Integration Engineer, you will hold a leading role in defining, characterizing, integrating, and verifying these instruments and their consumable devices.

Responsibilities

• Defining and interpreting technical requirements and design specifications

• Developing test methods and verifying them

• Driving design verification campaigns from planning to execution and reporting

• Leading cross-functional teams to identify and document design and process risks

• Coaching development teams on product development process and design controls.

• Leading or participating in characterization, investigation, optimization, and integration activities of instruments and consumable devices

• Reviewing existing product development process documents, performing gap assessments, and working with process experts to resolve issues

• Designing experiments and analyzing experimental data

• Participating in execution of design verification activities

• Mentoring less experienced members of the team

• Contributing to creation of architecture documents

Qualifications

Come join us if you’re looking for a company where you have the opportunity to pursue your interests across functions and disciplines and grow professionally. In our team, a job title is not considered the final definition of who you are, but the starting point. We are looking for someone who has:

• Degree in mechanical engineering, bioengineering, biomedical engineering, or systems engineering. Different degrees with relevant experience will be considered

• Bachelor's degree with 6+ years of applicable industry experience, Master’s degree with 4+ years of applicable industry experience, or Ph.D. with 2+ years of applicable industry experience

• Experience in hardware development and verification in a regulatory environment; medical device and complex consumable experience preferred

• Proven ability to identify, assess, and solve technical problems

• Strong soft skills for resolving technical disagreements, driving alignments, resolving conflict, and managing change

• Strong written and verbal communication skills to interact with technical and non-technical audiences

• Experience with design verification including planning, designing studies, writing protocol and reports

• Experience with test method development

• Experience with failure modes and effects analysis (FMEAs)

• Working knowledge of statistical methods and design of experiments (DOE)

• Familiarity with microfluidics systems preferred

• Experience with DNA sequencing preferred

• Experience working in a matrix organization preferred

Relocation benefits are not offered for this role. The expected salary range for this position based on the primary location of Santa Clara, CA is $ 125,000 and $155,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed here: Benefits

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company’s health and safety obligations and/or applicable law or guidelines.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us at US.Accommodation@roche.com.