Lead Scientist, Structural Biology and Biophysics (Blue Sky Kinases) Job at St. Jude Children's Research Hospital
We are seeking a highly driven Lead Scientist with broad interest in structural biology and biophysics to oversee, organize, and coordinate the activities of multiple researchers in a dynamic, comprehensive, inter-disciplinary initiative at the Department of Structural Biology, St. Jude Children's Research Hospital.
The Blue Sky Initiative "Seeing the Invisible in Protein Kinases" is supported by US $50 million in institutional funding (more information in the St. Jude Strategic Plan 2022–2027). This large-scale project aims to leverage ultra-high field NMR, complemented with cryoEM, X-ray crystallography, data-science and computational approaches, to characterize the conformational landscape of the human kinome. We expect this initiative to have a profound impact on the field, transforming our understanding of protein kinases and creating new therapeutic opportunities.
We are looking for an accomplished and enthusiastic scientist to take a key leadership role in this project. This is a high-level staff position, and the Lead Scientist will:
- coordinate the activities of over 50 scientists across different teams who perform biochemistry, NMR, cryoEM, X-ray crystallography, and computational analyses of different kinases.
- organize and integrate the data generated by those teams.
- participate in hiring additional staff scientists, as necessary.
- be the contact point for PIs and team leaders for information on all ongoing projects.
- identify kinases of biological and medical interest as targets.
- prepare materials for reports, presentations and publications.
- take a lead on organizing internal scientific meetings.
- attend relevant international scientific meetings.
- interact with other teams within St. Jude to identify scientific opportunities relevant for this project.
Applicants should have a Ph.D. in a relevant subject; a background in structural biology or biophysics and a strong interest in molecular mechanisms are highly desirable. In addition, the ideal candidate should have a track record of exceptional organizational and problem-solving abilities; outstanding communication skills; be able to absorb, synthesize and integrate different types of information; work independently; and thrive on a highly collaborative and fast-moving environment.
St. Jude Children’s Research Hospital offers a remarkable opportunity to perform cutting-edge research with outstanding institutional support and exceptional shared core facilities in an environment of open collaboration, educational advancement and training opportunities. St. Jude is consistently ranked on Fortune Magazine’s and Glassdoor’s “100 Best Places to Work” for companies with 1,000 or more employees. We are located in the heart of Memphis, Tennessee, a vibrant and friendly city at the historic American crossroads of music, trade, food, and culture. Mild winters and beautiful green outdoor spaces are part of the reasons why Forbes recently named Memphis the 4th happiest city in which to work. Cost of living and high quality of life are other attractions; Money magazine listed Memphis as one of the least expensive cities in which to raise a child. St. Jude facilities and salaries are highly competitive.
Minimum Education
- Bachelor's degree in relevant scientific area is required
Minimum Experience
- Twelve (12) years of relevant post-degree work experience is required
- Ten (10) years of relevant post-degree experience is required with a Master's degree
- Eight (8) years of relevant post-degree work experience is required with a PhD
Other Information
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St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.Please Note :
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